Welcome to the SCOOTT Trial
The SCOOTT trial investigates how best to treat basal thumb osteoarthritis once a patient has been referred to secondary care. ​
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The animation below provides further information on why we are running the trial and patient activities involved in participation.
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Summary of the Trial
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Base of thumb osteoarthritis affects 1 in 5 people over the age of 40, causing thumb pain, tenderness and stiffness which negatively impacts activities of daily living and quality of life.
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There are several treatments available for base of thumb osteoarthritis, each with different advantages and disadvantages but we do not yet have strong evidence about which is best overall.
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The SCOOTT trial is looking to recruit 656 adults with symptomatic base of thumb osteoarthritis presenting to surgeons at 20 NHS hospitals across the United Kingdom
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Participants will be randomly allocated to receive either trapeziectomy (removing the trapezium, a bone at the base of the thumb), CMCJR (carpometacarpal joint replacement) or enhanced non-surgical management (The ENGAGE Package)
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Participants will complete 7 questionnaires over a period of 18-months following entry into the trial.
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A summary of trial findings will be available for participants and be communicated to them, unless participants do not want to receive this.
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